Analysis of Mishel's Uncertainty in the Theory of Disease evidence-based to real-world situations. For example, in the reconceptualized version of Mishel's theory, the main hypothesis is related to uncertainty and how individuals function when in a chaotic state (Mishel, 2011). A fluctuation in control can create chaos and at the same time increase an individual's willingness to change (Alligood, 2014). Uncertainty occurs when an individual fails to adequately classify a disease-related event due to a lack of sufficient cues (Alligood, 2014). This uncertainty in life can take many forms. Mishel describes uncertainty in the form of unpredictability, inconsistent information, complexity, and ambiguity (Alligood, 2014). Theory in Practice Mishel's uncertainty in disease theory has been used repeatedly in nursing practice for chronic and acute conditions. The American Nurses Association has a strict recommendation to be familiar with the code of ethics for nurses, the ethical framework for MS, and all other practice settings (ANA, 2015). Having a solid knowledge base regarding these principles is key for healthcare professionals to honor education and research in nursing practice activities (ANA, 2015). MS nursing practice, education, and research require knowledge of ethical considerations. MS, the disease, does not discriminate and neither should nursing, the profession, in order to advance evidence-based practice and quality nursing care beyond the 21st century. Consequently, an experienced nurse today will apply Mishel's uncertainty to disease theory by considering the ethics, personal biases, and multicultural elements of the individual, support person, and community (Alligood,

Topic > Analysis of Mishel's Uncertainty in the Theory of Disease evidence-based to real-world situations. For example, in the reconceptualized version of Mishel's theory, the main hypothesis is related to uncertainty and how individuals function when in a chaotic state (Mishel, 2011). A fluctuation in control can create chaos and at the same time increase an individual's willingness to change (Alligood, 2014). Uncertainty occurs when an individual fails to adequately classify a disease-related event due to a lack of sufficient cues (Alligood, 2014). This uncertainty in life can take many forms. Mishel describes uncertainty in the form of unpredictability, inconsistent information, complexity, and ambiguity (Alligood, 2014). Theory in Practice Mishel's uncertainty in disease theory has been used repeatedly in nursing practice for chronic and acute conditions. The American Nurses Association has a strict recommendation to be familiar with the code of ethics for nurses, the ethical framework for MS, and all other practice settings (ANA, 2015). Having a solid knowledge base regarding these principles is key for healthcare professionals to honor education and research in nursing practice activities (ANA, 2015). MS nursing practice, education, and research require knowledge of ethical considerations. MS, the disease, does not discriminate and neither should nursing, the profession, in order to advance evidence-based practice and quality nursing care beyond the 21st century. Consequently, an experienced nurse today will apply Mishel's uncertainty to disease theory by considering the ethics, personal biases, and multicultural elements of the individual, support person, and community (Alligood,