Cancer, diabetes, heart disease – these are all diseases that people believe are at least partially caused by stress. Studies have shown that cellular stress also leads to the development of these diseases. While there are a variety of illnesses that stress can cause, I believe that all stress is good in small doses. Research shows that it is possible to build stress resistance, both mentally and physically, through exposure to stress. This is healthy because stress is inevitable in our changing world; having resistance to stress is better than facing an onslaught of stress someday in the future. Stress, as described by Hans Selye, is a condition the body encounters when it responds to various physical or emotional pressures. These various physical or emotional pressures are usually called "stressors". Stressors can include anything from an irritating bright light to an environmental change; both can cause changes in our bodies that indicate stress. Unfortunately, with stress comes impending thoughts of cancer and other life-threatening illnesses. However, Selye's research has shown that stress's companion is our body's adaptive responses. He coined the theory of the "General Adaptation Syndrome" (GAS) which consists of three parts: the "Alarm Reaction", the Resistance Phase and the Exhaustion Phase. The “alarm reaction” is characterized by tissue breakdown (tissue catabolism), low blood sugar levels (hypoglycemia), erosion of the stomach or intestines, and other symptoms: the body is in a state of alarm. The resistance phase is usually able to reverse these symptoms; this demonstrates the adaptability of living organisms to cope with change. However, if stressors continue to affect the body, the body ends up… middle of paper… up to Ubc13. TRAF2 can then activate NF-κB, a transcription factor that can induce the production of immune genes. As you can see, our bodies do a lot to stay healthy and functional. I believe that even if our cells are not exposed to stress, it is inevitable that there will be unfolded proteins due to mutations. Having a system like this would allow our cells to function better. I also believe we can incorporate cell apoptosis into cancer research. If the mechanisms of cell apoptosis are confirmed, researchers will be able to combine such mechanisms with anti-tumor therapy to kill harmful cells. Therefore, although cellular stress and "common" stress can lead to various diseases, I think that the resistance we develop because of this is good for us. Of course, I don't think a large amount of stress is good, but a small amount of anything usually doesn't hurt.
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