Importance of GCP (Good Clinical Practice) and ICH Guidelines: GCP (Good Clinical Practice) is an established international standard for the design, conduct, monitoring and recording of studies clinicians. GCP guarantees the accuracy and credibility of the reported results. It also ensures that the rights and integrity of the subject are protected and kept secret and that the data collected is reliable. Here it is very necessary to understand the reasons that led to the formation of the GCP-ICH guidelines. The Nuremberg Code: In 1947, the Nuremberg Code was established after German doctors were accused of conducting experiments on human subjects without their permission or consent. This code clearly stated that to conduct medical experiments on human subjects, they must have given their consent and be fully aware of the risks of the experiment. The Declaration of Helsinki: In 1965, the World Medical Association (WMA) developed guidelines for ethical principles regarding human experimentation. It focused on protecting the rights of human subjects. It was the basis of the ICH-GCP guidelines...