One of humanity's greatest achievements, a joint venture between 14 countries, worth billions of dollars and hosting, past and present, 157 astronauts , the International Space Station can be considered the most important project on Earth. The ISS has brought advances in many areas of study, and chemistry is no exception. The question is: how was chemistry involved in the ISS? First, the science of chemistry was used to refine and create new materials that the ISS would be made of. Second, chemistry was used to create conditions conducive to life on the ISS; many chemical compounds were created for use in the life support system. Finally, the ISS has brought many innovations in the field of chemistry, further improving human life. Without further ado, let's explore the applications of chemistry in space through the ISS. Before the first ISS module, Zarya, was sent into space, many chemists and engineers were developing and perfecting the materials that would make up the ISS. Before the idea of ​​an international station in space arose, the Long Duration Exposure Facility, a cylindrical structure the size of a school bus designed to test the exposure of different materials in space, was sent into space with the Space Shuttle Challenger on the mission STS-. 41-C on April 6, 1984, providing NASA with research data on materials that are still used today (Kinard). The LDEF carried over 10,000 material samples, consisting of virtually any material even remotely considered for future optical, mechanical, electrical, and other systems on future spacecraft, but most of the probe was covered in chrome-anodized aluminum thermal blankets and silver Teflon (ibid.). . The result of the experiment benefits spaceflight materials eng...... middle of paper ......ade Any scientific breakthroughs? - Yahoo Answers." Web log comment. Has the International Space Station made any scientific discoveries? Philippine Traveler, 2009. Web. April 21, 2014. Kinard, William H. "Overview." Long Duration Exposure Facility (LDEF) Archive System .NASA Langley Research Center, 29 October 2007. Web. 21 April 2014.Kinard, William H. "Technical Discipline Area: Materials." LDEF (Long Duration Exposure Facility) Archive System. NASA Langley Research Center, 04 April 2001. Web. April 21, 2014. "Life Support Systems in Space." . Web. 21 April 2014. “Water quality in orbit: U tests H20 disinfection on space station".. 2014.