Crop losses, especially along the post-harvest food supply chain, have been identified as a major cause of food shortage problems in most part of developing countries and in Nigeria in particular. Farmers who grow vegetables, such as those who grow tomatoes, often experience large product losses resulting in a waste of resources, a reduction in income and, ultimately, their well-being. This study examined the effects of post-harvest losses on the welfare of 107 tomato farmers in Ogbomosho selected through a multi-stage sampling procedure. The analytical tools used in the study include descriptive statistics, gross margin analysis, Ordinary Least Square (OLS) and regression model. The findings revealed that the majority of tomato farmers were men, married and without formal education. The average gross margin values ​​of N3, 229.45 and N72, 905.80 were obtained with and without post-harvest losses for tomato farmers respectively. This implied a 95.5% post-harvest loss suffered by farmers. Household size and the total value of post-harvest losses were found to significantly affect per capita income and therefore negatively affect the well-being of tomato farmers. The study recommends that farmers engaged in tomato production receive adequate training on post-harvest crop management techniques. Furthermore, priority should be given to investments in post-harvest processing technologies and the establishment of processing industries, especially in production areas.Keywords: post-harvest loss, tomato, welfare, farmers, Nigeria.INTRODUCTIONGlobal efforts in the fight against hunger to increase farmers' income and improve food security, especially in the world's poorest countries, should give priority to the issue of crop losses (FAO, 2010). Th...... middle of paper ......ndian Res. J. est. Edu. 9(3), September 2009. Muhammad RH, Hionu GC, Olayemi FF (2012). Assessment of post-harvest knowledge of fruit and vegetable farmers in Garun Mallam LGA of Kano, Nigeria. internal J. Develop. Hold up. 1(2):510-515.Mujib ur R, Naushad K, Inayatullah J (2007). Postharvest Losses in Tomato Crop: A Case in Peshawar Valley. Sarhad J. Agric. 23(4):1279-1284.Seid H, Hassen B, Yitbarek WH (2013). Assessment of post-harvest losses of commercial horticultural crops in Southern Wollo, Ethiopia “Challenges and Opportunities”. Food Science Quality Management. 17:34-39.Seisuke K, Neelima S (2008). Tomato (Solanum lycopersicum): a model fruit crop., Shankara N, Joep Van Lidt de Jeude, Marja de Goffau, Martin H, Barbara Van Dam (2005). Tomato cultivation, production, processing and marketing. Agrodok 17, Agromisa Foundation and CTA, Wageningen, 2005.