IntroductionMyasthenia Gravis is a chronic autoimmune disease that weakens muscles. The name MG comes from the Latin words meaning severe muscle weakness. In 1672, Thomas Willis was the first to describe a patient suffering from myasthenia gravis. Over the years, periodic case descriptions of this disease were published in the 1900s. The disease remained a mystery until 1960, when Simpson suggested that myasthenia gravis was caused by antibodies to the acetylcholine (ACh) receptor. Patrick and Lindstorm both demonstrated that myasthenia gravis is autoimmune in origin by testing rabbits immunized with Torpedo ACh receptors that became myasthenic. Today, myasthenia gravis is one of the best understood neurological disorders. This has led to a general understanding of the disease as associated cause, risk factors, complications, incidence, affected organ systems, signs and symptoms, diagnosis and treatments, which greatly improve the length and quality of life of these individuals. Homeostatic ImbalanceThis chronic autoimmune disease is characterized by varying degrees of skeletal muscle weakness. Weakness increases during periods of activity and improves after rest. Normally, the muscles that control eye and eyelid movement, facial expressions, chewing, speaking and swallowing are affected first. Causes Myasthenia gravis is a disorder of neuromuscular transmission. To understand the causes of myasthenia gravis, we must first describe what creates normal neuromuscular transmission. Neuromuscular transmission is where nerve cells connect to muscles. In a healthy individual there is an impulse from the nerve to the nerve endings that release a neurotransmitter, ACh. This neurotran...... middle of paper ......, exposure to any kind of infection like cold and flu should be avoided. Treatment There is no cure for myasthenia gravis, but treatment can help relieve signs and symptoms. There are many studies conducted on myasthenia patients with different medications, alone or in combination with existing drug therapies, to see if they are effective. Other studies include the long-term benefit of thymectomy compared to medical therapy alone for patients who do not have tumors. Prognosis Patients' symptoms and signs usually stabilize or improve after three years. The prognosis of myasthenia gravis has improved dramatically with the introduction of treatments, and most patients become symptom-free if properly treated. However, most patients must continue taking the tablets for life as symptoms generally return if they stop treatment
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