Many people love the fact that they can enjoy a normal life because their brain works accordingly. Well not everyone has the gift of normality. In this harsh world people die of all kinds of diseases and things that are undetectable or even curable because they have unknown origins. Many of the world's diseases such as HIV, AIDS, some cases of multiple sclerosis and muscular dystrophies. Among these life-threatening and life-threatening disorders, Creutzfeldt-Jakob disease, otherwise known as (CJD), takes precedence. Creutzfeldt-Jakob disease (CJD) is an unusual, degenerative, consistently terminal brain disease, typically with onset of symptoms around age 60. This disease has been classified into three main categories: 1) Sporadic CJD, 2) Hereditary CJD, 3) Acquired CJD. In sporadic CJD, the disease occurs even if the affected person does not have any known risk factors that could cause the onset of the disease. the disease. This sudden CJD is undoubtedly the most frequently diagnosed form of Creutzfeldt-Jakob disease. This statistically represents at least 85% of CJD cases. For this reason, in the United States alone, there are fifty to sixty deaths per year due to sporadic CJD. Similar data is observed in other countries such as Australia, Canada and the United Kingdom. In hereditary CJD, the infected person has inherited an abnormal gene due to a family history of the disease or undergoes a test in which the results are positive for a genetic mutation. which is associated with Creutzfeldt-Jakob disease. Around 5-10% of Creutzfeldt-Jakob disease cases in the US are hereditary and the UK has a population of around 58 million and there are only a few cases of deaths due to genetic CJD in a year. CJD, the disease is transmitted through exposure to brain or nervous system tissue, usually through certain medical procedures. Acquired CJD is also very rare; So far there has been no concrete evidence that CJD is transmissible through casual encounters with a CJD patient. Since Creutzfeldt-Jakob disease was first discovered in 1920, fewer than 1% of cases have been diagnosed as acquired CJD. Creutzfeldt-Jakob disease (CJD) belongs to a family of human and animal diseases known as transmissible spongiform encephalopathies (TSEs). Spongiform refers to the distinctive appearance of contaminated brains, which fill with holes to resemble sponges when viewed under a microscope.